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KMID : 1038620200380010052
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Radiation Oncology Journal
2020 Volume.38 No. 1 p.52 ~ p.59
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Magnetic resonance image-based tomotherapy planning for prostate cancer
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Jung Sang-Hoon
Kim Jin-Sung
Chung Yoon-Sun
Keserci Bilgin
Pyo Hong-Ryull
Park Hee-Chul
Park Won
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Abstract
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Purpose: To evaluate and compare the feasibilities of magnetic resonance (MR) image-based planning using synthetic computed tomography (sCT) versus CT (pCT)-based planning in helical tomotherapy for prostate cancer.
Materials and Methods: A retrospective evaluation was performed in 16 patients with prostate cancer who had been treated with helical tomotherapy. MR images were acquired using a dedicated therapy sequence; sCT images were generated using magnetic resonance for calculating attenuation (MRCAT). The three-dimensional dose distribution according to sCT was recalculated using a previously optimized plan and was compared with the doses calculated using pCT.
Results: The mean planning target volume doses calculated by sCT and pCT differed by 0.65% ± 1.11% (p = 0.03). Three-dimensional gamma analysis at a 2%/2 mm dose difference/distance to agreement yielded a pass rate of 0.976 (range, 0.658 to 0.986).
Conclusion: The dose distribution results obtained using tomotherapy from MR-only simulations were in good agreement with the dose distribution results from simulation CT, with mean dose differences of less than 1% for target volume and normal organs in patients with prostate cancer.
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KEYWORD
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Prostatic neoplasms, Magnetic resonance imaging, Helical tomotherapy
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